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Penyakit Autoimun Lebih Banyak Menyerang Wanita, Hormon Jadi Pemicunya

"Autoimmune Diseases More Commonly Affect Women, Hormones Being the Trigger"

Autoimmune Diseases Affect More Women, Hormones Are the Trigger

Dream - One of the diseases that often confuses many people because the symptoms are not always the same is autoimmune. There are also many variants of this disease, ranging from allergies, lupus, psoriasis, and many more.

Autoimmune Diseases Affect More Women, Hormones Are the Trigger

The following is the translation of the given 'Bahasa' text to 'English' while preserving any HTML tags: "Autoimmune diseases can occur when the immune system attacks the body's tissues. Did you know, Sahabat Dream, that studies have shown that autoimmune conditions affect about 8 percent of people worldwide, with 78 percent of them being women."

Autoimmune Diseases Affect More Women, Hormones Are the Trigger

Doctor Rajeev Gupta, Director of Internal Medicine at CK Birla Hospital, Delhi, said that hormonal influence and chromosomal differences are two main reasons why autoimmune diseases occur more frequently in women.

"Women experience significant hormonal fluctuations throughout their lives, especially during puberty, pregnancy, and menopause. These changes, particularly in estrogen levels, can affect the immune system and make women more vulnerable to misguided attacks on healthy tissues (autoimmunity)," said Doctor Rajeev.

"Chromosomes of Men and Women"

Regarding chromosomes, females have two X chromosomes, while males have one X and one Y chromosome. Doctor Rajeev explained that there is a theory stating that the process of inactivating one X chromosome in each female cell is sometimes incomplete. This can cause an excess of certain genes on the active X chromosome, which may potentially trigger an overly active immune and autoimmune response.

"Autoimmune disorders in women may be caused by the interruption of their second X chromosome by molecules that confuse the immune system. This may explain why conditions such as multiple sclerosis and lupus are more common in women than men," said Dr. Yathish GC, Senior Consultant - Rheumatology, Aster Whitefield Hospital, Bengaluru."

Appears in the 30s

Generally, autoimmune diseases become more common after women reach their thirties, coinciding with hormonal changes associated with aging. There are also some autoimmune diseases that can occur at any age.

Muncul di Usia 30-an
Autoimmune Diseases Affect More Women, Hormones Are the Trigger

"Several diseases such as multiple sclerosis usually begin between the ages of 20 and 40, while other diseases such as rheumatoid arthritis start appearing in the 40s or early 50s," said Doctor Yathish."

Experts call for the implementation of a healthy lifestyle such as balanced diet, quitting smoking, avoiding alcohol, stress management, maintaining fitness, and avoiding environmental pollution can reduce the potential occurrence of autoimmunity in women. Report by Aykaputri Amalia Rahmani/ Source: GulfToday

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