Apart from Titi Kamal, the soap opera "Satu Cinta Dua Hati" also stars a number of well-known celebrities, such as Lucky Perdana, Rifky Balweel, Annisa Kaila, and Zeid Mujib Yahya. This soap opera tells the story of Salwa (Titi Kamal), a woman who has to struggle to raise her two children, Nayla (Annisa Kaila) and Arsya (Zeid Mujib Yahya), on her own after her husband, Fahri (Rifky Balweel), leaves her to work in another city.

Salwa and her two children were accused of killing a man and were chased by thugs. They were then helped by Ridho, a wealthy man who also had a son. Ridho decided to help Salwa and her two children. Salwa and Ridho grew closer and eventually fell in love. However, their relationship did not go smoothly because Fahri suddenly returned. Salwa had to choose between Ridho, the man who had helped her and her two children, or Fahri, her husband who had left her.

However, during the funeral of his father, Ridho met a woman from his past who made Salwa curious about her identity. Bu Lidya, in a harsh tone, said that the woman is a special woman in Ridho's life. Again, Salwa, feeling uneasy, could only watch Ridho's closeness with that woman from a distance. Who is that woman actually?