Death can have various causes. Deaths resulting from suicide, accidents, or even murder are known as unnatural deaths. On the other hand, there are deaths referred to as natural or death by natural causes. Deaths that occur due to natural reasons should be seen as part of the human life cycle. There are many factors that can be considered as natural causes of human death.

Some health problems such as heart attacks, cancer, and infections can be considered as natural causes of death because they occur within the body without interference from external factors. This concept also applies when someone dies due to natural aging processes, which are characterized by a decline in bodily functions, energy, or appetite over time. Natural death occurs when the human body experiences a slowdown in function and eventually vital organs cease to operate.

The main cause of natural death most common in humans worldwide is ischemic heart disease or coronary artery disease (CAD). Coronary artery disease occurs when the arteries that supply blood to the heart harden and narrow due to the buildup of plaque and cholesterol. This disease accounts for about 16% of total deaths worldwide. In addition, there are also strokes and chronic obstructive pulmonary disease (COPD). Stroke occurs when blood flow to the brain is disrupted, while COPD is a group of lung diseases including chronic bronchitis and emphysema that make it difficult for someone to breathe.

The cause of death refers to direct factors that cause someone to die, such as coronary heart disease, stroke, or COPD. Meanwhile, the manner of death describes how someone dies, such as suicide, accident, or undetermined death. A death certificate prepared by a doctor usually records the direct or ultimate cause of death, as well as underlying factors or health history that trigger the event.